The complex relationship between alcohol and chronic pain

"Unrelieved chronic pain is considered a key factor contributing to the maintenance of alcohol use disorder (AUD). The mechanisms responsible for chronic pain associated with chronic alcohol consumption are still unknown. Thus, our goal was to evaluate the development of chronic pain in a mouse model of alcohol dependence and investigate the role of neuroinflammation in this chronic condition."

Vittoria Borgonetti, Amanda J. Roberts, Michal Bajo, Nicoletta Galeotti, Marisa Roberto. Chronic alcohol induced mechanical allodynia by promoting neuroinflammation: a mouse model of alcohol‐evoked neuropathic pain.. British Journal of Pharmacology, 2023; DOI: 10.1111/bph.16091

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