Molecular switch for addiction behavior: Newly discovered mechanism determines how strongly mice respond to cocaine

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December 19, 2021

Molecular switch for addiction behavior: Newly discovered mechanism determines how strongly mice respond to cocaine

A molecular switch influences addiction behavior and determines how strong the response to addictive drugs is. A research team made the discovery in mice treated with cocaine. The researchers demonstrated that the protein Npas4 regulates the structure and function of nerve cells that control addiction behavior in mice. If the quantity of Npas4 was reduced in an experiment, the animals' response to cocaine was much weaker.

https://pubmed.ncbi.nlm.nih.gov/34661342/

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